Poster, European Association for Cancer Research, Lisbon, Portugal
This research is based on our new computational pipeline that we used to quanitfy and report intratumoral heterogeneity in MSI status using single-cell RNA sequencing data.
Talk, World Cancer Congress, Geneva, Switzerland
This talk shared research that was published with my adviser on microsatellite instability detection tools used in next-generation sequencing data. We found very interesting results, most notably that microsatellite instability tools did not have the same performance across different sequencing types, and that some tools, despite literature stating otherwise, had very low performance in general.
Talk, Queen's University, Belfast, UK
In this talk, I explained surprising benchmarking results for the leading microsatellite instability tools. While still in an early stage at this point, this provided a great opportunity to discuss the idea that the leading microsatellite instability detection tools were not performing as described in literature.
Tutorial, University of Galway, Galway, Ireland
In this tutorial, I described how to use hierarchical F-statistics (Wright, 1931) to explore genetic variation in a population. This tutorial explored different populations of hippogryphs, and what could be discerned by determining if variation was structured at the individual level (FIS), the regional level (FSR), or at the site level (FST). Also briefly discussed is the idea of genetic rescue.
Talk, Washington State University, Pullman, WA, USA
This was a public defense of my master’s thesis proposal. I described my use of traditional population genetics theory to infer recent population bottlenecks and the impact on genome evolution in an invasive asexual snail.